| Tuesday, June 10, 2003 |
| 8:30 a.m. |
Welcome and Introductions
Samuel A. Wells, Jr., M.D.
President, General Motors Cancer Research Foundation
|
| 8:40 a.m. |
Keynote Address and Conference Overview
Irving L. Weissman, M.D.
Karel and Avice Beekhuis Professor of Cancer Biology
Professor of Pathology and Biological Sciences
Stanford University School of Medicine, Stanford, California |
Session 1: Developmental Biology of Stem Cells
Moderator: Phillip A. Sharp, Ph.D.
Awards Assembly Chairman, General Motors Cancer Research Foundation
Institute Professor and Director, The McGovern Institute for
Brain Research
Center for Cancer Research, Massachusetts Institute of Technology
Cambridge, Massachusetts |
| 9:30-9:50 a.m. |
"Regulation of Stem Cell Self-Renewal
vs. Differentiation in the Male Germ Line"
Margaret T. Fuller, Ph.D.
Professor Departments of Developmental Biology and Genetics
Chair, Department of Developmental Biology
Stanford University School of Medicine, Stanford, California |
| 9:50-10:00 a.m. |
Discussion |
| 10:00-10:20 a.m. |
Judith E. Kimble, Ph.D.
Department of Biochemistry
College of Agricultural and Life Sciences, The University of
Wisconsin
Madison, Wisconsin |
| 10:30-11:00 a.m. |
Break |
Session II: Embryology of Stem Cells
Moderator: Stuart H. Orkin, M.D.
David G. Nathan Professor of Pediatrics
Chair, Department of Pediatric Oncology
Dana Farber Cancer Institute Children's Hospital
Harvard Medical School, Boston, Massachusetts |
| 11:00-11:20 a.m. |
"Stem Cells and Developmental Pathways"Janet
Rossant, Ph.D.
Senior Investigator, Samuel Lunenfeld Research Institute
Department of Medical Genetics and Microbiology
Mount Sinai Hospital, University of Toronto, Toronto, Canada |
| 11:20-11:30 a.m. |
Discussion |
| 11:30-11:50 a.m. |
"Pluripotency and Lineage Restriction
of ES Cells"
Austin Smith, Ph.D.
Professor, Institute for Stem Cell Research
The University of Edinburgh, Edinburgh, Scotland |
| 11:50 a.m.-Noon |
Discussion |
| Noon-12:20 p.m. |
"Nuclear Cloning, Stem Cells, and the
Reprogramming of the Genome"
Rudolph Jaenisch, Ph.D.
Member, Whitehead Institute for Biomedical Research
Professor of Biology, Massachusetts Institute of Technology,
Cambridge, Massachusetts |
| 12:20-12:30 p.m. |
Discussion |
| 12:30-1:15 p.m. |
Lunch Break |
Session III: Organ Stem Cells
Moderator: Suzanne Cory, B.Sc., Ph.D.
Director, The Walter and Eliza Hall Institute of Medical Research,
Melbourne, Australia |
| 1:15-1:35 p.m. |
David J. Anderson, Ph.D.
Professor of Biology
Investigator, Howard Hughes Medical Institute
California Institute of Technology, Pasadena, California |
| 1:35-1:45 p.m. |
Discussion |
| 1:45-2:05 p.m. |
"Nuclear Transfer and Embryonic Stem Cells"
Peter Mombaerts, M.D., Ph.D.
Associate Professor
Head, Laboratory of Developmental Biology and Neurogenetics
The Rockefeller University, New York, New York |
| 2:05-2:15 p.m. |
Discussion |
| 2:15-2:35 p.m. |
"Adult Neural Stem Cells"
Fred (Rusty) H. Gage, Ph.D.
Professor of Biology
Laboratory of Genetics
The Salk Institute for Biological Studies, La Jolla, California |
| 2:35-2:45 p.m. |
Discussion
Moderator: Charles J. Sherr, M.D., Ph. D.
Chairman, Department of Tumor Cell Biology
St. Jude Children's Research, Memphis, Tennessee
|
| 2:45-3:05 p.m. |
Constance L. Cepko, Ph.D.
Professor of Genetics
Investigator, Howard Hughes Medical Center
Harvard Medical School, Boston Massachusetts |
| 3:05-3:15 p.m. |
Discussion |
| 3:15-3:35 p.m. |
"How Do Intestinal Stem Cells Protect
their DNA From Genotoxic Damage"
Christopher S. Potten, BSc, MSc, PhD, DSc
Professor of Stem Cell Biology
Manchester University, Epistem Limited, Manchester, UK |
| 3:35-3:45 p.m. |
Discussion |
| 3:45 p.m. |
Adjourn |
| Wednesday, June 11, 2003 |
Session IV: Hematopoietic Stem Cells
Moderator: Alan Bernstein, Ph.D.
President, Canadian Institutes of Health Research, Ottawa, Canada
|
| 9:00-9:20 a.m. |
Stuart H. Orkin, M.D.
David G. Nathan Professor of Pediatrics
Chair, Department of Pediatric Oncology
Dana Farber Cancer Institute Children's Hospital
Harvard Medical School, Boston, Massachusetts |
| 9:20-9:30 a.m. |
Discussion |
| 9:30-9:50 a.m. |
"Control of Lineage Commitment in Hematopoietic
Stem Cells"
Donald Metcalf, M.D.
Professor, Division of Cancer Biology and Hematology
The Walter & Eliza Hall Institute of Medical Research, Victoria,
Australia |
| 9:50-10:00 a.m. |
Discussion |
| 10:00-10:30 a.m. |
Break |
Session V: Stem Cells and Therapy
Moderator: Edison Liu, M.D.
Executive Director, Genome Institute of Singapore
Professor of Medicine, National University of Singapore |
| 10:30-10:50 a.m. |
"Complexity of the Human Stem Cell Compartment:
Implications for Therapy"
John E. Dick, Ph.D.
Director, Program in Stem Cell Biology
Division of Cell and Molecular Biology
Toronto General Research Institute, Toronto, Canada |
| 10:50-11:00 a.m. |
Discussion |
| 11:00-11:20 a.m. |
"Isolation and Characterization of Breast
Cancer Stem Cells"
Michael F. Clarke, Ph.D.
Professor of Internal Medicine
Division, Hematology/Oncology
University of Michigan School of Medicine, Ann Arbor, Michigan
|
| 11:20-11:30 a.m. |
Discussion |
| 11:30-11:50 a.m. |
Ian Wilmut, Ph.D.
Roslin Institute, Roslin BioCentre, Midlothian, Scotland |
| 11:50 a.m.-Noon |
Discussion |
| Noon-1:00 p.m. |
Lunch Break |
| 1:00-3:00 p.m. |
Laureate Lectures |
